Thermo Proteome Discoverer 1.1

Proteome Discoverer software is a comprehensive tool for proteomic data analysis. It supports multiple dissociation techniques, quantitation technologies, and database search algorithms for more confident and comprehensive protein identification and characterization. The Proteome Discoverer Daemon facilitates automated data analysis for greater productivity.
Key Features and Benefits:
* Multiple database search capability provides the option of applying multiple search algorithms (SEQUEST, Z-Core, Mascot, etc.) and combining their outputs to maximize and cross-validate results
* Support for multiple dissociation techniques (CID, ETD, and HCD) and the ability to combine their results helps identify more PTMs and increase confidence in those identifications
* Support for isobaric mass tagging (TMT, iTRAQ), and HeavyPeptide techniques enable relative or absolute quantitation
* A Mascot-based peptide mass fingerprinting workflow leverages high-mass-accuracy MALDI data
* False Discovery Rate (FDR) determination validates protein IDs
* Wizards and customizable proteomics workflows simplify analysis of MSn data from raw spectra through protein annotation
* Automated annotation of identified proteins with GO classifications, PTMs, and literature references from public databases illustrates biological context
* Creative data interrogation strategies such as generating inclusion and exclusion lists and import those lists directly into instrument methods enable more effective location of low-level sample components
* Support for data standards developed by the HUPO Proteomics Standards Initiative (PSI) facilitates data comparison, exchange, and verification
* SRF file import wizard provides a seamless transition from the Thermo Scientific BioWorks platform
* Robust Proteome Discoverer software platform can be expanded through integration of custom software tools